Charles angioma biography
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Cincinnati Childr
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The dural angioleiomyoma harbors frequent GJA4 mutation and a distinct DNA methylation profile
- Research
- Open access
- Published:
- Arnault Tauziède-Espariat1,2na1,
- Thibaut Pierre1,3na1,
- Michel Wassef4,
- David Castel5,6,
- Florence Riant7,
- Jacques Grill5,6,
- Alexandre Roux2,8,
- Johan Pallud2,8,
- Edouard Dezamis8,
- Damien Bresson9,
- Sandro Benichi10,
- Thomas Blauwblomme10,
- Djallel Benzohra11,
- Guillaume Gauchotte12,
- Celso Pouget12,
- Sophie Colnat-Coulbois13,
- Karima Mokhtari14,
- Corinne Balleyguier3,
- Frédérique Larousserie15,
- Volodia Dangouloff-Ros16,
- Nathalie Boddaert16,
- Marie-Anne Debily5,6,
- Lauren Hasty1,
- Marc Polivka4,
- Homa Adle-Biassette4,
- Alice Métais1,2,
- Emmanuèle Lechapt1,17,
- Fabrice Chrétien1,
- Felix Sahm18,19,
- Philipp Sievers18,19,
- Pascale Varlet1,2 on behalf of
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Acta Neuropathologica Communicationsvolume 10, Article number: 81 (2022) Cite this article
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Abstract
The International Society for the Study of Vascular Anomalies (ISSVA) has defined four vascular lesions in the central nervous system (CNS): arteriovenous malformations, cavernous angiomas (also known as cerebral
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Spider angioma
Medical condition
A spider angioma or spider naevus (plural: spider naevi), also nevus araneus, is a type of telangiectasis[2] (swollen, spider-like blood vessels on the skin) found slightly beneath the skin's surface, often containing a central red spot and deep reddish extensions (see Blood color) which radiate outwards like a spider's web or a spider's legs. They are common and often benign, presenting in around 10–15% of healthy adults and young children.[3] However, having more than three spider angiomas is likely to be abnormal and may be a sign of liver disease and/or hepatitis C (HCV virus);[4] it also suggests the probability of esophageal varices.[5]
Signs and symptoms
[edit]Spider angiomas are found only in the distribution of the superior vena cava, and are thus commonly found on the face, neck, upper part of the torso, and arms.[citation needed]
Cause
[edit]Spider angiomas form due to failure of the sphincteric muscle surrounding a cutaneousarteriole. The central red dot is the dilated arteriole and the red "spider legs" are small capillaries carrying away the freely flowing blood. If momentary pressure is applied, it is possible to see the emptied capillaries refilling from t